Jack and Vanessa are an expectant couple that moves into the most haunted fixer-upper in New Orleans — a house with a deadly demonic curse. Things soon spiral out of control for Jack and Vanessa, as well as their-not-so-helpfulneighbor FResnel, Vanessas friendly psychiatrist (Michael Ian Black), Vanessas Wiccan sister Marjorie and the detectives assigned to look into the rising body count. Only the Vaticans elite exorcism team can save them — or can they?