El juego es desarrollado por FreeStyleGames disponible para el Xbox 360,PLAYSTATION3y Nintendo Wii. Esta versión incluye nuevos modos de juego para la opción multijugador (se puede jugar con dos tornamesas) donde se podránt ener batallas de DJ’s e incluir a un jugador para que rapee, cante o grite. El juego trae nuevas mezclas exclusivas y también podrás hacer las tuyas en el modo Freestyle. Como en la versión 5 del Guitar Hero el modo de juego PartyPlay permitirá que jugadores adicionales puedan entrar y participar en las canciones a placer.

Se podrá comprar eljuego en un Party Bundle con dos tornamesas y un micrófono.

El modo de juego "Empire Mode" te permitirá jugar al DJ exitoso con el poder de dominar la industria delentretenimiento musical.

Les dejamos las 100canciones que son parte del set list:

o 2Pac feat. Dr. Dre and Roger Troutman -"California Love Remix"

o 50 Cent – "In Da Club"

o Adamski – "Killer"

o Afrika Bambaataa and The Soul Sonic Force- "Planet Rock"

o Armand Van Helden – "I Want Your Soul"

o A-Trak – "Say Whoa"

o B.o.B feat. Bruno Mars – "Nothin’ On You"

o Basement Jaxx – "Where’s Your Head At"

o BlakRoc feat. Pharoahe Monch & RZA -"Dollaz & Sense"

o Busta Rhymes – "Put Your Hands Where MyEyes Can See"

o Calvin Harris – "I’m Not Alone"

o Chamillionaire – "Ridin’"

o Chic – "Good Times"

o Chic – "Le Freak"

o Clinton Sparks, DJ Class, & JermaineDupri – "Favorite DJ"

o Daft Punk – "Human After All"

o Damian Marley – "Welcome To Jamrock"

o David Guetta & Chris Willis – "LoveIs Gone"

o David Guetta feat. Kid Cudi – "Memories"

o David Guetta vs. The Egg – "Love Don’tLet Me Go (Walking Away)"

o Deadmau5 – "Ghosts N Stuff"

o Deadmau5 & Kaskade – "I Remember"

o Deee-Lite – "Groove Is In The Heart"

o Dillinja and Skibadee – "Twist ‘Em Out"

o Dizzee Rascal & Armand Van Helden -"Bonkers"

o DJ Qbert – "Super Battle Breaks"

o DJ Shadow – "Midnight In A Perfect World"

o DJ Shadow feat. Q-Tip and Lateef TheTruth Speaker – "Enuff (DJ Fresh Remix)"

o Donna Summer – "Bad Girls"

o Edwin Starr – "War"

o Eminem – "Not Afraid"

o Estelle feat. Kanye West – "American Boy"

o Flo Rida – "Low"

o Flo Rida feat. Will.I.Am – "In The Ayer"

o Gorillaz feat. Mos Def & Bobby Womack- "Stylo"

o Grandmaster Flash & The Furious Fivefeat. Melle Mel & Duke Bootee – "The Message"

o Harold Faltermeyer – "Axel F"

o House Of Pain – "Jump Around"

o Iyaz – "Replay"

o Janet Jackson – "Nasty"

o Justice – "D.A.N.C.E."

o Justice – "Waters Of Nazareth"

o Kanye West – "Heartless"

o Kanye West – "Love Lockdown"

o Kaskade & Deadmau5 – "Move For Me"

o Kelis – "Acapella (David Guetta ExtendedMix)"

o Kool & The Gang – "Jungle Boogie"

o Lady Gaga – "Lovegame"

o Lady Gaga – "Bad Romance"

o Lady Gaga feat. Colby O’Donis – "JustDance"

o Lil Jon & The East Side Boyz feat.Ying Yang Twins – "Get Low"

o Lil’ Wayne – "Go DJ"

o Lil’ Wayne feat. Static Major -"Lollipop"

o LL Cool J – "I Can’t Live Without MyRadio"

o M.I.A. – "Galang"

o M|A|R|R|S – "Pump Up The Volume"

o Major Lazer feat. VYBZ Kartel – "Pon DeFloor"

o Malcolm McLaren – "Buffalo Gals"

o Metallica – "The Day That Never Comes"

o Missy Elliott – "Get Ur Freak On"

o MSTRKRFT feat. N.O.R.E. – "Bounce"

o Nas feat. Keri Hilson – "Hero"

o Naughty By Nature – "O.P.P."

o Nelly – "Hot In Herre"

o New Boyz – "You’re A Jerk"

o New Order – "Blue Monday"

o Newcleus – "Jam On It"

o Nightcrawlers – "Push The Feeling On (MKMix 95)"

o Orbital – "The Box"

o Pirate Soundsystem – "Bashy Bashy"

o Pitbull – "I Know You Want Me (CalleOcho)"

o Pussycat Dolls feat. Busta Rhymes -"Don’t Cha"

o Rihanna – "Pon De Replay"

o Rihanna – "Rude Boy"

o Robin S – "Show Me Love (StonebridgeRadio Edit)"

o Salt N Pepa – "Push It"

o Sam Cooke – "Chain Gang"

o Sam Sparro – "B&G" a/k/a "Black &Gold"

o Sean Paul – "Infiltrate"

o Sean Paul – "Get Busy"

o Snoop Dogg – "Who Am I (What’s My Name)?"

o Snow – "Informer"

o Soulja Boy Tell ‘Em – "Crank That (SouljaBoy)"

o Sparfunk & D-Code – "Apocalypse"

o Stevie Wonder – "Superstition"

o Talib Kweli – "Get By"

o The Chemical Brothers – "Leave Home"

o The Chemical Brothers feat. Q-Tip -"Galvanize"

o The Crystal Method – "Busy Child (StillBusy After All These Years Remix)"

o The Jackson 5 – "ABC"

o The Notorious B.I.G. feat. Mase &Diddy – "Mo’ Money, Mo’ Problems"

o The Prodigy – "Omen"

o The Prodigy – "Firestarter"

o Tiësto – "Speed Rail"

o Tiësto & Sneaky Sound System – "IWill Be Here"

o Tiësto vs Diplo – "Come On"

o Tiga – "You Gonna Want Me"

o Timbaland feat. Drake – "Say Something"

o Timbaland feat. Keri Hilson & D.O.E.- "The Way I Are"

o Tweet feat. Missy Elliott – "Oops (OhMy)"

o Walter Murphy – "A Fifth Of Beethoven"

o Warren G feat. Nate Dogg – "Regulate"

o Wayne Smith – "Under Mi Sleng Teng"

o Yeah Yeah Yeahs – "Heads Will Roll(A-Trak Remix )"

o Young Jeezy feat. Kanye West – "Put On"