Eight Rwandan children leave their families behind to embark on a life or death journey seeking high-risk heart surgery in Sudan. Their hearts ravaged by a treatable disease from childhood strep throat, the kids have only months to live. Open Heart reveals the intertwined endeavors of Dr. Emmanuel, Rwandas lone government cardiologist as he fights to save the lives of his young patients, and Dr. Gino, the Salam Centers fiercely opinionated head surgeon, who must also fight to save his hospital, Africas only link to life-saving free cardiac surgery for the millions who need it.